ABSTRACT
Topicality: In recent years interest to biologically active preparations of a phytogenesis is considerably increased. Tannins are very widespread group of biologically active agents of the plants, having various pharmacological properties (astringent, styp tic, antiinflammatory), and causing their broad application in m edicine.[1] Therefore the problem of determination of high quality of medicines and the medicinal plant raw materials containing this group of biologically active agents is very actual. The techniques, allowing to establish high quality of the raw materials containing tannins, were applied to raw materials of Rhizomata Bergeniae crassifoliae from an original derivative plant of a Bergenia crassifolia (L. ) Fritsch, genus of Bergenia. The purpose of this work: is to carry out a number of research works on studying of a chemical composition of the medicinal plant raw materials containing tannins, and to make a precise characteristic of these plants on the basis of the received results. According to a goal of this research the following tasks are defined: 1. To carry out the macroscopic and microscopical analysis of medicinal raw materials of Rhizomata Bergeniae crassifoliae 2. To define the main indicators of commodity research;3. To define quality and quantity biologically active agents in these plants. For the solution of tasks the following Methods: of the analysis were used:macroscopic, microscopical, phytochemicaland histochemical analysis, thin-layerchromatography and spectophotometery.Powder of Rhizomata Bergeniae crassifoliae(Krasnogorseleksredstva ltd. production) and crumbled of Rhizomata Bergeniae crassifoliae (the manufacturer of Ivan-Chay ltd.) were used as samples for this analysis.Results: According to pharmacopeia article “ Rhizomata Bergeniae crassifoliae “, for the specified raw materials are established the following numerical indicators: quantity tannins not less than 20%; humidity no more than 14%; total ash no more than 4%; ashes, insoluble in 10% Acidum hydrochloricum solution, no more than 0,5%. [2] The analyzed raw materials correspond to these indicators. As a result of carrying out histochemical and phytochemical reactions in rhizomes of a bergenia the following biologically active agents were found: arbutin, tannins (catechol, EGCG), polysaccharides.Conclusion: Medicinal plant raw materials ofKrasnogorseleksredstva ltd. and Ivan-Chay ltd.correspond to the general pharmacopeia article“Rhizomata Bergeniae crassifoliae”.References1. L.M. Fedoseeva. Study of tannins and aboveground vegetative organs Bergeniae crassifoliae (L. ) Fritsch native of Altai / L.M. Fedoseeva, E.V. Timochin // Chemistry of plant raw material. – 2003. - №1. – pp.73-77.2. State pharmacopeia Ed. XI. M.: Medicine, 1990. T.2. p. 399.3. State pharmacopeia Ed. XI. M.: Medicine, 1987. T.1. p. 335.4. G.P. Yakovlev. Rhizomata Bergeniae crassifoliae / G.P. Yakovlev, I.A. Samilina, L.V. Moshkova // Pharmacognozy. SPb.: SpecLit, 2006. pp. 556-558.5. I.M. Korenskaya. Qualitative and quantitativeanalysis of medicinal plant raw materials containing tannins. / I.M. Korenskaya, N.P. Ivanovskaya, I.E. Izmalkova // Medicinal plants and medicinal plant raw materials containing simple phenols, lignans, tannins. Voronezh, 2007. Pp. 48-51Methods: of the analysis were used: macroscopic, microscopical, phytochemical and histochemical analysis, thin laye r chromatography and